› 4v2a

X-ray diffraction
2.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180587 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Netrin receptor UNC5A Chain: A
Molecule details ›
Chain: A
Length: 303 amino acids
Theoretical weight: 33.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q6ZN44 (Residues: 1-303; Coverage: 34%)
Gene names: KIAA1976, UNC5A, UNC5H1
Sequence domains: Immunoglobulin I-set domain

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 25.83Å b: 87.77Å c: 133.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.328 0.327 0.344
Expression system: Homo sapiens

Quick links

Citations

16 review citations

Development and Arealization of the Cerebral Cortex.
Cadwell et al. (2019)
15 more

4 mentions without citation

Super-complexes of adhesion GPCRs and neural guidance receptors.
Jackson et al. (2016)
3 more