› 4wqj

X-ray diffraction
2.7Å resolution

Crystal Structure of CYP119 from Sulfolobus acidocaldarius, Collected at 298K and Complexed with 4-(4-bromophenyl)-1H imidazole

Released:
DOI: 10.2210/pdb4wqj/pdb
PDB entry 4wqj coloured by chain, front view.
PDB entry 4wqj coloured by chain, side view.
PDB entry 4wqj coloured by chain, top view.
Source organism: Sulfolobus acidocaldarius DSM 639
Entry author: Madrona Y

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176263 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome P450 119 Chain: A
Molecule details ›
Chain: A
Length: 368 amino acids
Theoretical weight: 42.92 KDa
Source organism: Sulfolobus acidocaldarius DSM 639
Expression system: Escherichia coli
UniProt:
  • Canonical: Q55080 (Residues: 1-368; Coverage: 100%)
Gene names: Saci_2081, cyp119
Sequence domains: Cytochrome P450
Structure domains: Cytochrome P450

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM
2 bound ligands:
Ligand 36Y 1 x 36Y
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P6322
Unit cell:
a: 168.68Å b: 168.68Å c: 76.35Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.169 0.166 0.211
Expression system: Escherichia coli

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