› 4wri

X-ray diffraction
1.4Å resolution

Crystal structure of okadaic acid binding protein 2.1

Released:
DOI: 10.2210/pdb4wri/pdb
PDB entry 4wri coloured by chain, front view.
PDB entry 4wri coloured by chain, side view.
PDB entry 4wri coloured by chain, top view.
Source organism: Halichondria okadai
Primary publication:
Crystal Structure of Okadaic Acid Binding Protein 2.1: A Sponge Protein Implicated in Cytotoxin Accumulation.
Ehara H, Makino M, Kodama K, Konoki K, Ito T, Sekine SI, Fukuzawa S, Yokoyama S, Tachibana K
Chembiochem (2015)
PMID: 25965326

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Okadaic acid binding protein 2-alpha Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 22.82 KDa
Source organism: Halichondria okadai
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2MHR1 (Residues: 2-190; Coverage: 100%)
Gene name: OABP2A
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand OKA 1 x OKA
1 modified residue:
Ligand MLY 16 x MLY

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: C2221
Unit cell:
a: 42.97Å b: 64.62Å c: 145.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.174 0.205
Expression system: Escherichia coli

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Citations

2 review citations

Marine natural products.
Blunt et al. (2017)
1 more