› 4wxl

X-ray diffraction
2.33Å resolution

Crystal structure of a peptide deformylase from Haemophilus influenzae complex with Actinonin

Released:
DOI: 10.2210/pdb4wxl/pdb
PDB entry 4wxl coloured by chain, front view.
PDB entry 4wxl coloured by chain, side view.
PDB entry 4wxl coloured by chain, top view.
Source organism: Haemophilus influenzae 86-028NP
Entry authors: Kishor C, Addlagatta A

Function and Biology Details

Reaction catalysed: 
Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175727 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide deformylase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 169 amino acids
Theoretical weight: 19.08 KDa
Source organism: Haemophilus influenzae 86-028NP
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q4QMV6 (Residues: 1-169; Coverage: 100%)
Gene names: NTHI0725, def
Sequence domains: Polypeptide deformylase
Structure domains: Peptide deformylase

Ligands and Environments

2 bound ligands:
Ligand NI 4 x NI
Ligand BB2 4 x BB2
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P21
Unit cell:
a: 41.201Å b: 79.85Å c: 98.168Å
α: 90° β: 97.99° γ: 90°
R-values:
R R work R free
0.176 0.172 0.241
Expression system: Escherichia coli BL21(DE3)

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