Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
NTP + H(2)O = NDP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
Protease 3C (preferred)
PDBe Complex ID:
PDB-CPX-140231 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein 2B
Molecule details ›
Chains: A, B
Length: 217 amino acids
Theoretical weight: 25.15 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 217 amino acids
Theoretical weight: 25.15 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P08617 (Residues: 765-981; Coverage: 10%)
