Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
DNA polymerase alpha (preferred)
PDBe Complex ID:
PDB-CPX-140802 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA polymerase alpha subunit B
Molecule details ›
Chains: A, C, E, G
Length: 598 amino acids
Theoretical weight: 66.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 598 amino acids
Theoretical weight: 66.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q14181 (Residues: 1-598; Coverage: 100%)
Sequence domains:
DNA polymerase alpha catalytic subunit
Molecule details ›
Chains: B, D, F, H
Length: 180 amino acids
Theoretical weight: 21.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA Polymerase alpha zinc finger
Structure domains: DNA Polymerase alpha, zinc finger
Length: 180 amino acids
Theoretical weight: 21.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P09884 (Residues: 1265-1444; Coverage: 12%)
Sequence domains: DNA Polymerase alpha zinc finger
Structure domains: DNA Polymerase alpha, zinc finger
