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X-ray diffraction
2.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble cytochrome b562; Type-1 angiotensin II receptor Chain: A
Molecule details ›
Chain: A
Length: 414 amino acids
Theoretical weight: 47.24 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0ABE7 (Residues: 23-127; Coverage: 99%)
  • Canonical: P30556 (Residues: 15-319; Coverage: 85%)
Gene names: AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B, cybC
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZD7 1 x ZD7
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLAC LCLS BEAMLINE CXI
Spacegroup: C2
Unit cell:
a: 72.8Å b: 41Å c: 167.7Å
α: 90° β: 99.4° γ: 90°
R-values:
R R work R free
0.231 0.228 0.274
Expression system: Spodoptera frugiperda

Quick links

Citations

43 review citations

Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.
Forrester et al. (2018)
42 more

86 mentions without citation

G protein-coupled receptors: structure- and function-based drug discovery.
Yang et al. (2021)
85 more