› 4yc5

X-ray diffraction
1.76Å resolution

Beta1 synthetic solenoid protein

Released:
DOI: 10.2210/pdb4yc5/pdb
PDB entry 4yc5 coloured by chain, front view.
PDB entry 4yc5 coloured by chain, side view.
PDB entry 4yc5 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Synthetic beta-solenoid proteins with the fragment-free computational design of a beta-hairpin extension.
MacDonald JT, Kabasakal BV, Godding D, Kraatz S, Henderson L, Barber J, Freemont PS, Murray JW
Proc Natl Acad Sci U S A 113 10346-51 (2016)
PMID: 27573845

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165360 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
beta1 Chain: A
Molecule details ›
Chain: A
Length: 235 amino acids
Theoretical weight: 24.68 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Structure domains: E3 ubiquitin-protein ligase SopA

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P4122
Unit cell:
a: 64.57Å b: 64.57Å c: 160.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.158 0.184
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Designing repeat proteins: a modular approach to protein design.
Parmeggiani et al. (2017)
6 more

2 mentions without citation

Designed for life: biocompatible de novo designed proteins and components.
Grayson et al. (2018)
1 more