› 4z6g

X-ray diffraction
2.65Å resolution

Structure of NT domain

Released:
DOI: 10.2210/pdb4z6g/pdb
PDB entry 4z6g coloured by chain, front view.
PDB entry 4z6g coloured by chain, side view.
PDB entry 4z6g coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
In vivo epidermal migration requires focal adhesion targeting of ACF7.
Yue J, Zhang Y, Liang WG, Gou X, Lee P, Liu H, Lyu W, Tang WJ, Chen SY, Yang F, Liang H, Wu X
Nat Commun 7 11692 (2016)
PMID: 27216888

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194025 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 40.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UPN3 (Residues: 74-421; Coverage: 5%)
Gene names: ABP620, ACF7, KIAA0465, KIAA0754, KIAA1251, MACF1
Sequence domains: Calponin homology (CH) domain

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43212
Unit cell:
a: 94.088Å b: 94.088Å c: 192.634Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.24
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Microtubules in 3D cell motility.
Bouchet et al. (2017)
10 more

1 mention without citation

In vivo epidermal migration requires focal adhesion targeting of ACF7.
Yue et al. (2016)