› 4z6k

X-ray diffraction
1.9Å resolution

Alcohol dehydrogenase from the antarctic psychrophile Moraxella sp. TAE 123

Released:
DOI: 10.2210/pdb4z6k/pdb
PDB entry 4z6k coloured by chain, front view.
PDB entry 4z6k coloured by chain, side view.
PDB entry 4z6k coloured by chain, top view.
Source organism: Moraxella sp. TAE123
Primary publication:
Structure and Dynamics of a Thermostable Alcohol Dehydrogenase from the Antarctic Psychrophile Moraxella sp. TAE123
Petratos K, Gessmann R, Daskalakis V, Papadovasilaki M, Papanikolau Y, Tsigos I, Bouriotis V
Acs Omega (2020)

Function and Biology Details

Reaction catalysed: 
A primary alcohol + NAD(+) = an aldehyde + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alcohol dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 346 amino acids
Theoretical weight: 36.69 KDa
Source organism: Moraxella sp. TAE123
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8GIX7 (Residues: 1-338; Coverage: 100%)
Gene name: adh
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 10 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P3221
Unit cell:
a: 136.573Å b: 136.573Å c: 210.832Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.21 0.233
Expression system: Escherichia coli BL21(DE3)

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