› 4zbm

X-ray diffraction
1.9Å resolution

Crystal structure of Drosophila cyclic nucleotide gated channel pore mimicking NaK mutant

Released:
DOI: 10.2210/pdb4zbm/pdb
PDB entry 4zbm coloured by chain, front view.
PDB entry 4zbm coloured by chain, side view.
PDB entry 4zbm coloured by chain, top view.
Source organism: Bacillus cereus ATCC 14579
Primary publication:
Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels.
Lam YL, Zeng W, Derebe MG, Jiang Y
J Gen Physiol 146 255-63 (2015)
PMID: 26283200

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182541 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 97 amino acids
Theoretical weight: 10.69 KDa
Source organism: Bacillus cereus ATCC 14579
Expression system: Escherichia coli
UniProt:
  • Canonical: Q81HW2 (Residues: 20-110; Coverage: 79%)
Gene name: BC_0669
Sequence domains: Ion channel
Structure domains: Helix Hairpins

Ligands and Environments

2 bound ligands:
Ligand K 5 x K
Ligand BA 2 x BA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: I4
Unit cell:
a: 67.907Å b: 67.907Å c: 89.799Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.236
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Dhakshnamoorthy et al. (2016)

1 mention without citation

Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels.
Lam et al. (2015)