› 4zdg

X-ray diffraction
3.2Å resolution

Structure of the Adenovirus 14p1 knob domain

Released:
DOI: 10.2210/pdb4zdg/pdb
PDB entry 4zdg coloured by chain, front view.
PDB entry 4zdg coloured by chain, side view.
PDB entry 4zdg coloured by chain, top view.
Source organism: Human adenovirus 14p1
Primary publication:
Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1.
Wang H, Ducournau C, Saydaminova K, Richter M, Yumul R, Ho M, Carter D, Zubieta C, Fender P, Lieber A
J Virol 89 10841-59 (2015)
PMID: 26292319

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112765 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenoviral fibre protein knob domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 215 amino acids
Theoretical weight: 23.91 KDa
Source organism: Human adenovirus 14p1
Expression system: Escherichia coli
UniProt:
  • Canonical: D6BP13 (Residues: 121-323; Coverage: 63%)
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P63
Unit cell:
a: 112.414Å b: 112.414Å c: 79.538Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.2 0.246
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Immune Responses to Viral Gene Therapy Vectors.
Shirley et al. (2020)
6 more

2 mentions without citation

Intracellular Signaling and Desmoglein 2 Shedding Triggered by Human Adenoviruses Ad3, Ad14, and Ad14P1.
Wang et al. (2015)
1 more