4zkc

X-ray diffraction
3.15Å resolution

The chemokine binding protein of orf virus complexed with CCL7

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-160348 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Chemokine binding protein Chain: A
Molecule details ›
Chain: A
Length: 276 amino acids
Theoretical weight: 30.37 KDa
Source organism: Orf virus (strain NZ2)
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2F862 (Residues: 17-286; Coverage: 94%)
Sequence domains: 35kD major secreted virus protein
C-C motif chemokine 7 Chain: B
Molecule details ›
Chain: B
Length: 82 amino acids
Theoretical weight: 9.8 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P80098 (Residues: 24-99; Coverage: 100%)
Gene names: CCL7, MCP3, SCYA6, SCYA7
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P43212
Unit cell:
a: 77.43Å b: 77.43Å c: 181.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.263 0.26 0.327
Expression system: Homo sapiens