› 5agq

Solution NMR

Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes

Released:
DOI: 10.2210/pdb5agq/pdb
PDB entry 5agq coloured by chain, ensemble of 20 models, front view.
PDB entry 5agq coloured by chain, ensemble of 20 models, side view.
PDB entry 5agq coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes.
Anosova I, Melnik S, Tripsianes K, Kateb F, Grummt I, Sattler M
Nucleic Acids Res 43 5208-20 (2015)
PMID: 25916849

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193785 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain adjacent to zinc finger domain protein 2A Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 13.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UIF9 (Residues: 543-650; Coverage: 6%)
Gene names: BAZ2A, KIAA0314, TIP5
Sequence domains: Methyl-CpG binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: ARIA2, CNS
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

The new (dis)order in RNA regulation.
Järvelin et al. (2016)
6 more

1 mention without citation

A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes.
Anosova et al. (2015)