5anm

X-ray diffraction
2.85Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-208610 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (6 distinct):
IMMUNOGLOBULIN G Chains: A, C, L
Molecule details ›
Chains: A, C, L
Length: 217 amino acids
Theoretical weight: 22.93 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Structure domains: Immunoglobulins
IMMUNOGLOBULIN G Chains: B, D, H
Molecule details ›
Chains: B, D, H
Length: 229 amino acids
Theoretical weight: 24.75 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Structure domains: Immunoglobulins
Immunoglobulin heavy constant epsilon Chains: E, F, G
Molecule details ›
Chains: E, F, G
Length: 242 amino acids
Theoretical weight: 27.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01854 (Residues: 211-427; Coverage: 40%)
Gene name: IGHE
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P3221
Unit cell:
a: 140.957Å b: 140.957Å c: 244.448Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.196 0.26
Expression systems:
  • Cricetulus griseus
  • Homo sapiens