› 5ao5

X-ray diffraction
2.48Å resolution

Endo180 D1-4, monoclinic form

Released:
DOI: 10.2210/pdb5ao5/pdb
PDB entry 5ao5 coloured by chain, front view.
PDB entry 5ao5 coloured by chain, side view.
PDB entry 5ao5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Insights into Collagen Uptake by C-type Mannose Receptors from the Crystal Structure of Endo180 Domains 1-4.
Paracuellos P, Briggs DC, Carafoli F, Lončar T, Hohenester E
Structure 23 2133-42 (2015)
PMID: 26481812

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193652 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type mannose receptor 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 482 amino acids
Theoretical weight: 54.59 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UBG0 (Residues: 35-511; Coverage: 33%)
Gene names: CLEC13E, ENDO180, KIAA0709, MRC2, UPARAP
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand NA 4 x NA
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 126.37Å b: 92.37Å c: 127.65Å
α: 90° β: 100.31° γ: 90°
R-values:
R R work R free
0.196 0.194 0.244
Expression system: Homo sapiens

Quick links

Citations

1 review citation

uPARAP/Endo180: a multifaceted protein of mesenchymal cells.
Gucciardo et al. (2022)
10 other articles