Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-152954 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
E3 ubiquitin-protein ligase CBL-B
Molecule details ›
Chains: A, B, C
Length: 307 amino acids
Theoretical weight: 35.91 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 307 amino acids
Theoretical weight: 35.91 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q3TTA7 (Residues: 38-343; Coverage: 31%)
Sequence domains:
- CBL proto-oncogene N-terminal domain 1
- CBL proto-oncogene N-terminus, EF hand-like domain
- CBL proto-oncogene N-terminus, SH2-like domain
Insulin receptor substrate 1
Molecule details ›
Chain: E
Length: 5 amino acids
Theoretical weight: 662 Da
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 5 amino acids
Theoretical weight: 662 Da
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: P35569 (Residues: 606-610; Coverage: 0%)
