Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Protein Vpr and Importin subunit alpha-1 (preferred)
PDBe Complex ID:
PDB-CPX-156540 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-1
Molecule details ›
Chains: A, B
Length: 460 amino acids
Theoretical weight: 49.89 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 460 amino acids
Theoretical weight: 49.89 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P52293 (Residues: 70-529; Coverage: 87%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Protein Vpr
Molecule details ›
Chains: C, D, E, F
Length: 12 amino acids
Theoretical weight: 1.39 KDa
Source organism: HIV-1 M:B_89.6
Expression system: Not provided
UniProt:
Length: 12 amino acids
Theoretical weight: 1.39 KDa
Source organism: HIV-1 M:B_89.6
Expression system: Not provided
UniProt:
- Canonical: Q73369 (Residues: 85-96; Coverage: 13%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL26B1
Spacegroup:
P21
Expression systems:
- Escherichia coli
- Not provided
