Function and Biology Details
Reactions catalysed:
2 glutathione + ROOH = glutathione disulfide + H(2)O + ROH
Acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Peroxiredoxin-6 (preferred)
PDBe Complex ID:
PDB-CPX-151612 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxiredoxin-6
Molecule details ›
Chains: A, B, C, D, E, F
Length: 224 amino acids
Theoretical weight: 25.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
UniProt:
Sequence domains:
Structure domains:
Length: 224 amino acids
Theoretical weight: 25.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
UniProt:
- Canonical:
P30041 (Residues: 1-224; Coverage: 100%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 4A
Spacegroup:
P212121
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
