› 5bpw

X-ray diffraction
3.4Å resolution

Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain

Released:
DOI: 10.2210/pdb5bpw/pdb
PDB entry 5bpw coloured by chain, front view.
PDB entry 5bpw coloured by chain, side view.
PDB entry 5bpw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain.
Cronin NB, Yang J, Zhang Z, Kulkarni K, Chang L, Yamano H, Barford D
J Mol Biol 427 3300-3315 (2015)
PMID: 26343760

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193825 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anaphase-promoting complex subunit 4 Chain: A
Molecule details ›
Chain: A
Length: 843 amino acids
Theoretical weight: 95.96 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9UJX5 (Residues: 1-808; Coverage: 100%)
Gene names: ANAPC4, APC4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P4212
Unit cell:
a: 139.181Å b: 139.181Å c: 156.106Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.22 0.275
Expression system: Trichoplusia ni

Quick links

Citations

2 review citations

Insights into APC/C: from cellular function to diseases and therapeutics.
Zhou et al. (2016)
1 more

1 mention without citation

Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain.
Cronin et al. (2015)