› 5buo

X-ray diffraction
2.31Å resolution

A receptor molecule

Released:
DOI: 10.2210/pdb5buo/pdb
PDB entry 5buo coloured by chain, front view.
PDB entry 5buo coloured by chain, side view.
PDB entry 5buo coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Gao C, Crespi GAN, Gorman MA, Nero TL, Parker MW, Miles LA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138395 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Soluble APP-beta Chains: A, B
Molecule details ›
Chains: A, B
Length: 342 amino acids
Theoretical weight: 39.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P05067 (Residues: 370-710; Coverage: 45%)
Gene names: A4, AD1, APP
Sequence domains:
Structure domains: Amyloid precursor protein, E2 domain

Ligands and Environments

Carbohydrate polymer : NEW Components: SGN, IDS
Carbohydrate polymer
7 bound ligands:
Ligand ZN 6 x ZN
Ligand CA 1 x CA
Ligand GOL 3 x GOL
Ligand ACT 1 x ACT
Ligand SCN 3 x SCN
Ligand SO4 1 x SO4
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: I212121
Unit cell:
a: 60.41Å b: 103.05Å c: 108.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.23 0.241
Expression system: Escherichia coli BL21

Quick links