Function and Biology Details
Reaction catalysed:
(1a) [protein]-N(6)-acetyl-L-lysine + NAD(+) = [protein]-N(6)-(1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl)-L-lysine + nicotinamide
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180079 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histone H3.3C
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.09 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
Length: 10 amino acids
Theoretical weight: 1.09 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
- Canonical:
Q6NXT2 (Residues: 6-14; Coverage: 7%)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial
Molecule details ›
Chain: A
Length: 309 amino acids
Theoretical weight: 34.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Sir2 family
Structure domains:
Length: 309 amino acids
Theoretical weight: 34.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9NTG7 (Residues: 118-399; Coverage: 71%)
Sequence domains: Sir2 family
Structure domains:
