› 5byd

X-ray diffraction
2.1Å resolution

Crystal structure of human ribokinase in P21 spacegroup

Released:
DOI: 10.2210/pdb5byd/pdb
PDB entry 5byd coloured by chain, front view.
PDB entry 5byd coloured by chain, side view.
PDB entry 5byd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Park J, Chakrabarti J, Singh B, Gupta RS, Junop MS

Function and Biology Details

Reaction catalysed: 
ATP + D-ribose = ADP + D-ribose 5-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190599 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribokinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 330 amino acids
Theoretical weight: 35.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H477 (Residues: 1-322; Coverage: 100%)
Gene names: RBKS, RBSK
Sequence domains: pfkB family carbohydrate kinase
Structure domains: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase

Ligands and Environments

2 bound ligands:
Ligand NA 1 x NA
Ligand K 1 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P21
Unit cell:
a: 46.59Å b: 89.91Å c: 75.14Å
α: 90° β: 98.8° γ: 90°
R-values:
R R work R free
0.174 0.171 0.215
Expression system: Escherichia coli BL21(DE3)

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