› 5c2b

X-ray diffraction
1.4Å resolution

anti-CXCL13 parental scFv - 3B4

Released:
DOI: 10.2210/pdb5c2b/pdb
PDB entry 5c2b coloured by chain, front view.
PDB entry 5c2b coloured by chain, side view.
PDB entry 5c2b coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tu C, Bard J, Mosyak L

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-207255 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ig-like domain-containing protein; Immunoglobulin heavy variable 1-69D Chain: H
Molecule details ›
Chain: H
Length: 254 amino acids
Theoretical weight: 26.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A0B4J2H0 (Residues: 20-117; Coverage: 100%)
  • Canonical: A0A5C2GBJ8 (Residues: 1-111; Coverage: 99%)
Gene name: IGHV1-69D
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2221
Unit cell:
a: 131.9Å b: 133.5Å c: 44.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.194
Expression system: Homo sapiens

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