› 5c5c

X-ray diffraction
1.86Å resolution

Human metabotropic glutamate receptor 7, extracellular ligand binding domain

Released:
DOI: 10.2210/pdb5c5c/pdb
PDB entry 5c5c coloured by chain, front view.
PDB entry 5c5c coloured by chain, side view.
PDB entry 5c5c coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dong A, Dobrovetsky E, Hutchinson A, Tempel W, Edwards AM, Bountra C, Arrowsmith CH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172105 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metabotropic glutamate receptor 7 Chain: A
Molecule details ›
Chain: A
Length: 481 amino acids
Theoretical weight: 53.61 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q14831 (Residues: 37-513; Coverage: 54%)
Gene names: GPRC1G, GRM7, MGLUR7
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

4 bound ligands:
Ligand NAG 1 x NAG
Ligand GOL 1 x GOL
Ligand CA 2 x CA
Ligand UNX 11 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 106.175Å b: 101.203Å c: 55.318Å
α: 90° β: 110.46° γ: 90°
R-values:
R R work R free
0.208 0.206 0.248
Expression system: Spodoptera frugiperda

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