› 5c65

X-ray diffraction
2.65Å resolution

Structure of the human glucose transporter GLUT3 / SLC2A3

Released:
DOI: 10.2210/pdb5c65/pdb
PDB entry 5c65 coloured by chain, front view.
PDB entry 5c65 coloured by chain, side view.
PDB entry 5c65 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Pike ACW, Quigley A, Chu A, Tessitore A, Xia X, Mukhopadhyay S, Wang D, Kupinska K, Strain-Damerell C, Chalk R, Burgess-Brown NA, Edwards AM, Arrowsmith CH, Bountra C, Carpenter EP, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier family 2, facilitated glucose transporter member 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 481 amino acids
Theoretical weight: 52.52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P11169 (Residues: 1-474; Coverage: 96%)
Gene names: GLUT3, SLC2A3
Sequence domains: Sugar (and other) transporter
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

2 bound ligands:
Ligand 37X 9 x 37X
Ligand Y01 2 x Y01
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 63.55Å b: 116.03Å c: 99.75Å
α: 90° β: 106.91° γ: 90°
R-values:
R R work R free
0.206 0.205 0.223
Expression system: Spodoptera frugiperda

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