› 5c6w

X-ray diffraction
1.54Å resolution

anti-CXCL13 scFv - E10

Released:
DOI: 10.2210/pdb5c6w/pdb
PDB entry 5c6w coloured by chain, front view.
PDB entry 5c6w coloured by chain, side view.
PDB entry 5c6w coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tu C, Bard J, Mosyak L

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-229604 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin heavy variable 1-69D; Immunoglobulin lambda variable 2-14 Chains: H, J
Molecule details ›
Chains: H, J
Length: 264 amino acids
Theoretical weight: 27.49 KDa
Source organism: Homo sapiens
Expression system: Mammalia
UniProt:
  • Canonical: A0A0B4J2H0 (Residues: 20-117; Coverage: 100%)
  • Canonical: P01704 (Residues: 20-116; Coverage: 96%)
Gene names: IGHV1-69D, IGLV2-14
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

4 bound ligands:
Ligand CL 6 x CL
Ligand SO4 5 x SO4
Ligand EDO 29 x EDO
Ligand PEG 2 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 69.98Å b: 80.36Å c: 119.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.154 0.164
Expression system: Mammalia

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