Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158157 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cell division control protein 42 homolog
Molecule details ›
Chains: A, B, C, D
Length: 179 amino acids
Theoretical weight: 19.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 179 amino acids
Theoretical weight: 19.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P60953 (Residues: 1-177; Coverage: 93%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Ras GTPase-activating-like protein IQGAP2
Molecule details ›
Chains: E, F
Length: 387 amino acids
Theoretical weight: 44.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: GTPase-activator protein for Ras-like GTPase
Structure domains: GTPase Activation - p120gap; domain 1
Length: 387 amino acids
Theoretical weight: 44.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: Q13576 (Residues: 875-1258; Coverage: 24%)
Sequence domains: GTPase-activator protein for Ras-like GTPase
Structure domains: GTPase Activation - p120gap; domain 1
