Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Fibronectin and Tyrosine-protein kinase ABL1 (preferred)
PDBe Complex ID:
PDB-CPX-132603 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ugl-Y3
Molecule details ›
Chain: A
Length: 93 amino acids
Theoretical weight: 9.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins
Length: 93 amino acids
Theoretical weight: 9.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P02751 (Residues: 1538-1631; Coverage: 4%)
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins
Tyrosine-protein kinase ABL1
Molecule details ›
Chain: B
Length: 121 amino acids
Theoretical weight: 13.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 121 amino acids
Theoretical weight: 13.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P00519 (Residues: 112-232; Coverage: 11%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-E
Spacegroup:
C2
Expression system: Escherichia coli BL21(DE3)
