› 5dej

X-ray diffraction
1.37Å resolution

Transthyretin natural mutant A19D

Released:
DOI: 10.2210/pdb5dej/pdb
PDB entry 5dej coloured by chain, front view.
PDB entry 5dej coloured by chain, side view.
PDB entry 5dej coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Pereira HM, Ferreira P, Andrade C, Lima C, Palhano F, Foguel D

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-136167 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 116 amino acids
Theoretical weight: 12.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P02766 (Residues: 30-145; Coverage: 91%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21212
Unit cell:
a: 85.93Å b: 41.75Å c: 62.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.207
Expression system: Escherichia coli BL21

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