5dnf

X-ray diffraction
2.55Å resolution

Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
C-C motif chemokine 5 Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 65 amino acids
Theoretical weight: 7.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13501 (Residues: 27-91; Coverage: 96%)
Gene names: CCL5, D17S136E, SCYA5
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

Carbohydrate polymer : NEW Components: SGN, IDS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: C222
Unit cell:
a: 121.19Å b: 210.063Å c: 123.827Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.18 0.234
Expression system: Escherichia coli