5dps

X-ray diffraction
2Å resolution

Crystal structure of PLEKHM1 LIR-fused human GABARAP_2-117

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-131844 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-aminobutyric acid receptor-associated protein; Pleckstrin homology domain-containing family M member 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 132 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y4G2 (Residues: 627-638; Coverage: 1%)
  • Canonical: O95166 (Residues: 2-117; Coverage: 99%)
Gene names: FLC3B, GABARAP, HT004, KIAA0356, PLEKHM1
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P31
Unit cell:
a: 73.806Å b: 73.806Å c: 74.453Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.184 0.223
Expression system: Escherichia coli BL21(DE3)