5dwu

X-ray diffraction
3.97Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-211074 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Cytokine receptor common subunit beta Chain: A
Molecule details ›
Chain: A
Length: 224 amino acids
Theoretical weight: 25.46 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P32927 (Residues: 17-240; Coverage: 25%)
Gene names: CSF2RB, IL3RB, IL5RB
Sequence domains: GM-CSF/IL-3/IL-5 receptor common beta subunit, N-terminal
Cytokine receptor common subunit beta Chain: B
Molecule details ›
Chain: B
Length: 203 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P32927 (Residues: 241-443; Coverage: 23%)
Gene names: CSF2RB, IL3RB, IL5RB
Structure domains: Immunoglobulins
Fab - Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 24.13 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Fab - Light Chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: C2
Unit cell:
a: 99.953Å b: 71.289Å c: 221.234Å
α: 90° β: 102.71° γ: 90°
R-values:
R R work R free
0.29 0.288 0.33
Expression systems:
  • Spodoptera frugiperda
  • Homo sapiens