› 5dzl

X-ray diffraction
3.4Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146702 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carcinoembryonic antigen-related cell adhesion molecule 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 108 amino acids
Theoretical weight: 11.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13688 (Residues: 35-141; Coverage: 22%)
Gene names: BGP, BGP1, CEACAM1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P41212
Unit cell:
a: 75.76Å b: 75.76Å c: 147.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.232 0.288
Expression system: Escherichia coli

Quick links

Citations

176 review citations

Immune checkpoint blockade: a common denominator approach to cancer therapy.
Topalian et al. (2015)
175 more

6 mentions without citation

The science is in the data.
Helliwell et al. (2017)
5 more