› 5e1t

X-ray diffraction
2.8Å resolution

Crystal structure of TRAF1 TRAF domain

Released:
DOI: 10.2210/pdb5e1t/pdb
PDB entry 5e1t coloured by chain, front view.
PDB entry 5e1t coloured by chain, side view.
PDB entry 5e1t coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway.
Kim CM, Choi JY, Bhat EA, Jeong JH, Son YJ, Kim S, Park HH
Sci Rep 6 25526 (2016)
PMID: 27151821

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171521 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TNF receptor-associated factor 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 197 amino acids
Theoretical weight: 22.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13077 (Residues: 220-416; Coverage: 47%)
Gene names: EBI6, TRAF1
Sequence domains:
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P212121
Unit cell:
a: 75.352Å b: 79.404Å c: 108.982Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.211 0.262
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Structure of TRAF Family: Current Understanding of Receptor Recognition.
Park HH. (2018)
4 more

1 mention without citation

Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway.
Kim et al. (2016)