5e6p

X-ray diffraction
3.22Å resolution

PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-109721 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Plexin-B2 Chain: A
Molecule details ›
Chain: A
Length: 621 amino acids
Theoretical weight: 71.87 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: B2RXS4 (Residues: 1226-1842; Coverage: 34%)
Gene name: Plxnb2
Sequence domains:
Structure domains:
Rho guanine nucleotide exchange factor 11 Chain: B
Molecule details ›
Chain: B
Length: 88 amino acids
Theoretical weight: 9.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15085 (Residues: 42-125; Coverage: 6%)
Gene names: ARHGEF11, KIAA0380
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6222
Unit cell:
a: 126.152Å b: 126.152Å c: 211.465Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.254 0.297
Expression system: Escherichia coli