Function and Biology Details
Reaction catalysed:
Endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Heparanase complex (preferred)
PDBe Complex ID:
PDB-CPX-195099 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Heparanase 50 kDa subunit
Molecule details ›
Chain: A
Length: 389 amino acids
Theoretical weight: 43.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Glycosyl hydrolase family 79, N-terminal domain
Length: 389 amino acids
Theoretical weight: 43.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
Q9Y251 (Residues: 158-543; Coverage: 76%)
Sequence domains: Glycosyl hydrolase family 79, N-terminal domain
Heparanase 8 kDa subunit
