Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
mRNA cap guanine-N7 methyltransferase (preferred)
PDBe Complex ID:
PDB-CPX-128838 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
mRNA cap guanine-N7 methyltransferase
Molecule details ›
Chains: A, B, C, D
Length: 312 amino acids
Theoretical weight: 36.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: mRNA (guanine-N(7))-methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
Length: 312 amino acids
Theoretical weight: 36.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O43148 (Residues: 165-476; Coverage: 66%)
Sequence domains: mRNA (guanine-N(7))-methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
