Function and Biology Details
Reaction catalysed:
Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195088 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Molecule details ›
Chains: A, C, D
Length: 319 amino acids
Theoretical weight: 37.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Length: 319 amino acids
Theoretical weight: 37.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9Y233 (Residues: 718-1036; Coverage: 30%)
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Molecule details ›
Chain: B
Length: 320 amino acids
Theoretical weight: 37.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Length: 320 amino acids
Theoretical weight: 37.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9Y233 (Residues: 718-1036; Coverage: 30%)
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
