Function and Biology Details
Reaction catalysed:
Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Maltose/Cyclodextrin ABC transporter, substrate-binding protein
- Histone deacetylase domain
- Ureohydrolase domain superfamily
- Histone deacetylase domain superfamily
- Histone deacetylase class II, eukaryotic-type
- Solute-binding family 1, conserved site
- Bacterial-type extracellular solute-binding protein
- Haem oxygenase-like, multi-helical
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142601 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Histone deacetylase 6; Maltose/maltodextrin-binding periplasmic protein
Molecule details ›
Chains: A, B
Length: 745 amino acids
Theoretical weight: 81.52 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 745 amino acids
Theoretical weight: 81.52 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0AEX9 (Residues: 27-392; Coverage: 99%) - Canonical: Q9UBN7 (Residues: 479-835; Coverage: 29%)
Sequence domains:
