› 5ehd

X-ray diffraction
2.55Å resolution

Crystal structure of human nucleophosmin-core in complex with cytochrome c

Released:
DOI: 10.2210/pdb5ehd/pdb
PDB entry 5ehd coloured by chain, front view.
PDB entry 5ehd coloured by chain, side view.
PDB entry 5ehd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bernardo-Garcia N, Hermoso JA, Gonzalez-Arzola K, Diaz-Moreno I, De la Rosa MA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139205 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleophosmin Chains: A, B, C, D, E, F, G, H, I, J, a, b, c, d, e, f, g, h, i, j
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, a, b, c, d, e, f, g, h, i, j
Length: 116 amino acids
Theoretical weight: 12.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P06748 (Residues: 9-124; Coverage: 40%)
Gene names: NPM, NPM1
Sequence domains: Nucleoplasmin/nucleophosmin domain
Structure domains: Nucleoplasmin core domain

Ligands and Environments

1 bound ligand:
Ligand CL 4 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALBA BEAMLINE XALOC
Spacegroup: P21
Unit cell:
a: 58.799Å b: 179.72Å c: 104.3Å
α: 90° β: 94.32° γ: 90°
R-values:
R R work R free
0.167 0.164 0.229
Expression system: Escherichia coli BL21(DE3)

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