› 5emo

X-ray diffraction
3.03Å resolution

Structure of the star domain of T-STAR in complex with AUUAAA RNA

Released:
DOI: 10.2210/pdb5emo/pdb
PDB entry 5emo coloured by chain, front view.
PDB entry 5emo coloured by chain, side view.
PDB entry 5emo coloured by chain, top view.
Source organisms:
Primary publication:
Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Feracci M, Foot JN, Grellscheid SN, Danilenko M, Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez C
Nat Commun 7 10355 (2016)
PMID: 26758068

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131009 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
KH domain-containing, RNA-binding, signal transduction-associated protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 185 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75525 (Residues: 1-183; Coverage: 53%)
Gene names: KHDRBS3, SALP, SLM2
Sequence domains: Qua1 domain
RNA (5'-R(P*AP*UP*UP*AP*AP*A)-3') Chains: E, F
Molecule details ›
Chains: E, F
Length: 6 nucleotides
Theoretical weight: 1.88 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 51.601Å b: 79.967Å c: 53.831Å
α: 90° β: 101.05° γ: 90°
R-values:
R R work R free
0.226 0.221 0.269
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

9 review citations

Post-Transcriptional Regulation of Anti-Apoptotic BCL2 Family Members.
Cui et al. (2018)
8 more

1 mention without citation

Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Feracci et al. (2016)