› 5eop

X-ray diffraction
1.35Å resolution

Crystal structure of human Angiogenin at 1.35 Angstroms resolution

Released:
DOI: 10.2210/pdb5eop/pdb
PDB entry 5eop coloured by chain, front view.
PDB entry 5eop coloured by chain, side view.
PDB entry 5eop coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The ammonium sulfate inhibition of human angiogenin.
Chatzileontiadou DS, Tsirkone VG, Dossi K, Kassouni AG, Liggri PG, Kantsadi AL, Stravodimos GA, Balatsos NA, Skamnaki VT, Leonidas DD
FEBS Lett 590 3005-18 (2016)
PMID: 27483019

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137273 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03950 (Residues: 26-146; Coverage: 98%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: P21212
Unit cell:
a: 85.664Å b: 37.559Å c: 33.012Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.15 0.147 0.192
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 citation in other articles

Structure and function of the Toscana virus cap-snatching endonuclease.
Jones et al. (2019)
4 more

1 mention without citation

Structure of angiogenin dimer bound to double-stranded RNA.
Sievers et al. (2022)