› 5eqo

X-ray diffraction
2.4Å resolution

Human Angiogenin in complex with sulphate anions at an acidic solution

Released:
DOI: 10.2210/pdb5eqo/pdb
PDB entry 5eqo coloured by chain, front view.
PDB entry 5eqo coloured by chain, side view.
PDB entry 5eqo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The ammonium sulfate inhibition of human angiogenin.
Chatzileontiadou DS, Tsirkone VG, Dossi K, Kassouni AG, Liggri PG, Kantsadi AL, Stravodimos GA, Balatsos NA, Skamnaki VT, Leonidas DD
FEBS Lett 590 3005-18 (2016)
PMID: 27483019

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137273 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03950 (Residues: 25-145; Coverage: 98%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: P21212
Unit cell:
a: 82.04Å b: 37.45Å c: 42.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.186 0.25
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 citation in other articles

Structure and function of the Toscana virus cap-snatching endonuclease.
Jones et al. (2019)
5 more