Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-152688 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Myocyte-specific enhancer factor 2C
Molecule details ›
Chains: A, B, C, D
Length: 95 amino acids
Theoretical weight: 11.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: SRF-type transcription factor (DNA-binding and dimerisation domain)
Structure domains: Transcription factor, MADS-box
Length: 95 amino acids
Theoretical weight: 11.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q8CFN5 (Residues: 1-95; Coverage: 20%)
Sequence domains: SRF-type transcription factor (DNA-binding and dimerisation domain)
Structure domains: Transcription factor, MADS-box
Focal adhesion kinase 1
Molecule details ›
Chains: E, F, G
Length: 149 amino acids
Theoretical weight: 16.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Focal adhesion targeting region
Structure domains:
Length: 149 amino acids
Theoretical weight: 16.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P34152 (Residues: 904-1052; Coverage: 14%)
Sequence domains: Focal adhesion targeting region
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
P42212
Expression system: Escherichia coli BL21(DE3)
