Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133827 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Complement C3 beta chain
Molecule details ›
Chains: A, C
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01024 (Residues: 23-667; Coverage: 39%)
Sequence domains:
Complement C3b alpha' chain
Molecule details ›
Chains: B, D
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 749-1663; Coverage: 56%)
Sequence domains:
Complement decay-accelerating factor
Molecule details ›
Chains: E, F
Length: 194 amino acids
Theoretical weight: 21.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Sushi repeat (SCR repeat)
Length: 194 amino acids
Theoretical weight: 21.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P08174 (Residues: 97-285; Coverage: 55%)
Sequence domains: Sushi repeat (SCR repeat)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Expression system: Homo sapiens
