5gnv

X-ray diffraction
2.6Å resolution

Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-151889 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disks large homolog 4 Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.69 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31016 (Residues: 531-713; Coverage: 25%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains: Guanylate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases
MAP1A heavy chain Chain: B
Molecule details ›
Chain: B
Length: 26 amino acids
Theoretical weight: 2.8 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q9QYR6 (Residues: 1866-1891; Coverage: 1%)
Gene names: Map1a, Mtap1, Mtap1a

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 62.445Å b: 156.861Å c: 59.513Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.215 0.257
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided