› 5gph

Solution NMR

Solution structure of the Pin1-PPIase (S138A) mutant

Released:
DOI: 10.2210/pdb5gph/pdb
PDB entry 5gph coloured by chain, ensemble of 10 models, front view.
PDB entry 5gph coloured by chain, ensemble of 10 models, side view.
PDB entry 5gph coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Entry authors: Tochio N, Wang J, Tate S

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171737 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13526 (Residues: 51-163; Coverage: 69%)
Gene name: PIN1
Sequence domains: PPIC-type PPIASE domain
Structure domains: Chitinase A; domain 3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli BL21(DE3)

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