5grq

X-ray diffraction
1.58Å resolution

Crystal Structure of DHB domain of Daxx in complex with an ATRX peptide

Released:
Source organism: Homo sapiens
Entry author: Li H

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-155431 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Death domain-associated protein 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 10.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UER7 (Residues: 55-144; Coverage: 12%)
Gene names: BING2, DAP6, DAXX
Sequence domains: Daxx N-terminal Rassf1C-interacting domain
Structure domains: Daxx helical bundle domain
Transcriptional regulator ATRX Chains: C, D
Molecule details ›
Chains: C, D
Length: 30 amino acids
Theoretical weight: 3.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P46100 (Residues: 1256-1285; Coverage: 1%)
Gene names: ATRX, RAD54L, XH2

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 53.428Å b: 56.217Å c: 102.917Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.158 0.158 0.179
Expression system: Escherichia coli BL21(DE3)