› 5gtm

X-ray diffraction
2.9Å resolution

Modified human MxA, nucleotide-free form

Released:
DOI: 10.2210/pdb5gtm/pdb
PDB entry 5gtm coloured by chain, front view.
PDB entry 5gtm coloured by chain, side view.
PDB entry 5gtm coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET.
Chen Y, Zhang L, Graf L, Yu B, Liu Y, Kochs G, Zhao Y, Gao S
Nat Commun 8 15744 (2017)
PMID: 28548099

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149009 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-induced GTP-binding protein Mx1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 601 amino acids
Theoretical weight: 68.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20591 (Residues: 33-662; Coverage: 91%)
Gene name: MX1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 104.18Å b: 60.16Å c: 153.92Å
α: 90° β: 98.62° γ: 90°
R-values:
R R work R free
0.207 0.204 0.263
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Human MX2/MxB: a Potent Interferon-Induced Postentry Inhibitor of Herpesviruses and HIV-1.
Staeheli et al. (2018)
4 more

2 mentions without citation

Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET.
Chen et al. (2017)
1 more